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MRKMerck Sharp & Dohme LLCNot started yet

MK-2870-U01 Substudy 1: A Clinical Trial of Sacituzumab Tirumotecan to Treat Prostate Cancer (MK-2870-01A)

Metastatic Castration-resistant Prostate Cancer

2Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

  • 5 insiders sold shares within a month

    Since Aug 13, 2026 · was worth 5, fading over time

    +1.9
Worry score2

Score over time

Stage
Phase 1/2
Patients
290 (planned)
Started
Dec 14, 2026
Main results expected
Jun 29, 2032
Fully finished
Jun 29, 2032
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Efficacy Phase: Objective Response Rate (ORR)

    Measured over: Up to approximately 66 months

  • Efficacy Phase: Number of Participants Who Experience at Least One Adverse Event (AE)

    Measured over: Up to approximately 66 months

  • Efficacy Phase: Number of Participants Who Discontinue Study Intervention Due to an AE

    Measured over: Up to approximately 66 months

  • Safety Lead-In (Combination Arms Only): Number of Participants Who Experience a Dose-Limiting Toxicity (DLT)

    Measured over: Up to approximately 28 days

  • Safety Lead-In (Combination Arms Only): Number of Participants Who Experience at Least One AE

    Measured over: Up to approximately 66 months

  • Safety Lead-In (Combination Arms Only): Number of Participants Who Discontinue Study Intervention Due to an AE

    Measured over: Up to approximately 66 months

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • insider_selling_cluster: base 5, now 1.9, since 2026-08-13, fades (half-life)

Raw record changes

  • none yet

Trial ID NCT07908524 · record last updated 2026-11-02 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT07908524) ↗