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MRKMerck Sharp & Dohme LLCSigning up patients

A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) as First-line Maintenance Treatment of Cervical Cancer (MK-2870-036/TroFuse-036/GOG-3123/ENGOT-cx22)

Cervical Cancer

2Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

  • 5 insiders sold shares within a month

    Since Aug 13, 2026 · was worth 5, fading over time

    +1.9
Worry score2

Score over time

Stage
Phase 3
Patients
1,023 (planned)
Started
Jan 19, 2026
Main results expected
Oct 29, 2031
Fully finished
Oct 29, 2031
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Part 1 Safety Run-in: Number of Participants Who Experience One or More Adverse Events (AEs)

    Measured over: Up to approximately 69 months

  • Part 1 Safety Run-in: Number of Participants Who Discontinue Study Treatment Due to an AE

    Measured over: Up to approximately 66 months

  • Part 2 Maintenance Treatment: Progression-free Survival (PFS) per Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST 1.1) as Assessed by Blinded Independent Central Review (BICR)

    Measured over: Up to approximately 48 months

  • Part 2 Maintenance Treatment: Overall Survival (OS)

    Measured over: Up to approximately 60 months

Changes Tremor has spotted

  • Paperwork edit (contacts, locations, wording). Usually harmless.

    Spotted on Nov 6, 2026

Show details (technical version)

Score inputs

  • insider_selling_cluster: base 5, now 1.9, since 2026-08-13, fades (half-life)

Raw record changes

  • 2026-11-06 15:29 UTC · paperwork · other
    old: null
    new: null
    details: {"sections":["eligibilityModule","statusModule"]}

Trial ID NCT07216703 · record last updated 2026-11-06 · checked 2026-11-09 15:36 UTC

See the official record on ClinicalTrials.gov (NCT07216703) ↗