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MRKMerck Sharp & Dohme LLCSigning up patients

A Clinical Study of Calderasib (MK-1084) and Other Treatments for Participants With Non-Small Cell Lung Cancer (MK-1084-007/KANDLELIT-007)

Non-small Cell Lung Cancer

2Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

  • 5 insiders sold shares within a month

    Since Aug 13, 2026 · was worth 5, fading over time

    +1.9
Worry score2

Score over time

Stage
Phase 3
Patients
675 (planned)
Started
Oct 8, 2025
Main results expected
Dec 7, 2029
Fully finished
Aug 6, 2032
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Progression Free Survival (PFS) in Participants with Programmed Death-Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥1%

    Measured over: Up to approximately 48 months

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • insider_selling_cluster: base 5, now 1.9, since 2026-08-13, fades (half-life)

Raw record changes

  • none yet

Trial ID NCT07190248 · record last updated 2026-10-26 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT07190248) ↗