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MRKMerck Sharp & Dohme LLCSigning up patients

A Clinical Study of Ifinatamab Deruxtecan Based Treatment Combinations or as Monotherapy to Treat Metastatic Castrate Resistant Prostate Cancer (mCRPC) (MK-2400-01A/IDeate-Prostate02)

Castration-Resistant Prostatic Cancer · Metastasis

2Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

  • 5 insiders sold shares within a month

    Since Aug 13, 2026 · was worth 5, fading over time

    +1.9
Worry score2

Score over time

Stage
Phase 1/2
Patients
360 (planned)
Started
Jul 3, 2025
Main results expected
Oct 1, 2031
Fully finished
Oct 1, 2031
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Efficacy Phase: Number of Participants Who Experience One or More Dose-Limiting Toxicities (DLTs) - Combination Arms Only

    Measured over: Up to approximately 21 days

  • Efficacy Phase: Number of Participants Who Experienced an Adverse Event (AE)

    Measured over: Up to approximately 54 months

  • Efficacy Phase: Number of Participants Who Discontinued Study Intervention Due to an AE

    Measured over: Up to approximately 24 months

  • Efficacy Phase: Prostate-Specific Antigen (PSA) response rate

    Measured over: Up to approximately 54 months

  • Safety Lead-in Phase: Number of Participants Who Experience One or More Dose-Limiting Toxicities (DLTs) - Combination Arms Only

    Measured over: Up to approximately 21 days

  • Safety Lead-in Phase: Number of Participants Who Experienced an Adverse Event (AE) - Combination Arms Only

    Measured over: Up to approximately 21 days

  • Safety Lead-in Phase: Number of Participants Who Discontinued Study Intervention Due to an AE - Combination Arms Only

    Measured over: Up to approximately 21 days

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • insider_selling_cluster: base 5, now 1.9, since 2026-08-13, fades (half-life)

Raw record changes

  • none yet

Trial ID NCT06863272 · record last updated 2026-10-09 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT06863272) ↗