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MRKMerck Sharp & Dohme LLCSigning up patients

A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)

Triple Negative Breast Neoplasms

2Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

  • 5 insiders sold shares within a month

    Since Aug 13, 2026 · was worth 5, fading over time

    +1.9
Worry score2

Score over time

Stage
Phase 3
Patients
1,000 (planned)
Started
Mar 16, 2025
Main results expected
May 18, 2030
Fully finished
May 18, 2030
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Progression-Free Survival (PFS) (sac-TMT versus treatment of physician's choice (TPC); sac-TMT plus pembrolizumab versus TPC)

    Measured over: Up to ~39 months

  • Overall Survival (OS) (sac-TMT versus TPC)

    Measured over: Up to ~61 months

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • insider_selling_cluster: base 5, now 1.9, since 2026-08-13, fades (half-life)

Raw record changes

  • none yet

Trial ID NCT06841354 · record last updated 2026-10-13 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT06841354) ↗