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MRKMerck Sharp & Dohme LLCRunning, no new patients

A Study to Compare Sacituzumab Tirumotecan (MK-2870) Monotherapy Versus Treatment of Physician's Choice as Second-line Treatment for Participants With Recurrent or Metastatic Cervical Cancer (MK-2870-020/TroFuse-020/Gog-3101/ENGOT-cx20)

Cervical Cancer

2Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

  • 5 insiders sold shares within a month

    Since Aug 13, 2026 · was worth 5, fading over time

    +1.9
Worry score2

Score over time

Stage
Phase 3
Patients
686 (planned)
Started
Jul 24, 2024
Main results expected
Jun 15, 2028
Fully finished
Jun 15, 2028
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Objective Response Rate (ORR) in Sacituzumab Tirumotecan Run-in

    Measured over: Up to approximately 46 months

  • Number of Participants Experiencing One or More Adverse Events (AEs) in Sacituzumab Tirumotecan Run-in

    Measured over: Up to approximately 46 months

  • Number of Participants Discontinuing Study Treatment Due to an AE in Sacituzumab Tirumotecan Run-in

    Measured over: Up to approximately 46 months

  • Overall Survival (OS) in Phase 3 Portion

    Measured over: Up to approximately 35 months

Changes Tremor has spotted

  • Paperwork edit (contacts, locations, wording). Usually harmless.

    Spotted on Nov 9, 2026

Show details (technical version)

Score inputs

  • insider_selling_cluster: base 5, now 1.9, since 2026-08-13, fades (half-life)

Raw record changes

  • 2026-11-09 15:36 UTC · paperwork · other
    old: null
    new: null
    details: {"sections":["eligibilityModule","statusModule"]}

Trial ID NCT06459180 · record last updated 2026-11-09 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT06459180) ↗