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Tremor shows what changed in public records. It never tells anyone to buy or sell. Many trial edits are harmless paperwork. Data from ClinicalTrials.gov, the SEC, and the Federal Register.

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MRKMerck Sharp & Dohme LLCRunning, no new patients

A Study of Pembrolizumab (MK-3475) in Combination With Belzutifan (MK-6482) and Lenvatinib (MK-7902), or Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib, Versus Pembrolizumab and Lenvatinib, for Treatment of Advanced Clear Cell Renal Cell Carcinoma (MK-6482-012)

Carcinoma, Renal Cell

2Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

  • 5 insiders sold shares within a month

    Since Aug 13, 2026 · was worth 5, fading over time

    +1.9
Worry score2

Score over time

Stage
Phase 3
Patients
1,688 (final count)
Started
Apr 14, 2021
Main results expected
Feb 4, 2026
Fully finished
Apr 22, 2027
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Progression Free Survival (PFS) According to Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST 1.1) as Assessed by Blinded Independent Central Review (BICR)

    Measured over: Up to approximately 57 months

  • Overall Survival (OS)

    Measured over: Up to approximately 57 months

Changes Tremor has spotted

  • Paperwork edit (contacts, locations, wording). Usually harmless.

    Spotted on Nov 6, 2026

Show details (technical version)

Score inputs

  • insider_selling_cluster: base 5, now 1.9, since 2026-08-13, fades (half-life)

Raw record changes

  • 2026-11-06 15:29 UTC · paperwork · other
    old: null
    new: null
    details: {"sections":["referencesModule","statusModule"]}

Trial ID NCT04736706 · record last updated 2026-11-06 · checked 2026-11-09 15:36 UTC

See the official record on ClinicalTrials.gov (NCT04736706) ↗