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MRKMerck Sharp & Dohme LLCRunning, no new patients

Perioperative Enfortumab Vedotin (EV) Plus Pembrolizumab (MK-3475) Versus Neoadjuvant Chemotherapy for Cisplatin-Eligible Muscle Invasive Bladder Cancer (MIBC) (MK-3475-B15/ KEYNOTE-B15 / EV-304)

Bladder Cancer

12Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

  • Main results were due Oct 2025, none posted yet

    Counts until it's fixed

    +10
  • 5 insiders sold shares within a month

    Since Aug 13, 2026 · was worth 5, fading over time

    +1.9
Worry score12

Score over time

Stage
Phase 3
Patients
808 (final count)
Started
Apr 21, 2021
Main results expected
Oct 27, 2025
Fully finished
May 18, 2028
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Event-Free Survival (EFS)

    Measured over: Up to ~68 months

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • results_overdue: base 10, now 10, since 2025-10-27, no fading
  • insider_selling_cluster: base 5, now 1.9, since 2026-08-13, fades (half-life)

Raw record changes

  • none yet

Trial ID NCT04700124 · record last updated 2026-07-16 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT04700124) ↗