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Tremor shows what changed in public records. It never tells anyone to buy or sell. Many trial edits are harmless paperwork. Data from ClinicalTrials.gov, the SEC, and the Federal Register.

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MRKMerck Sharp & Dohme LLCRunning, no new patients

Study of Pembrolizumab (MK-3475) in Combination With Adjuvant Chemotherapy With or Without Radiotherapy in Participants With Newly Diagnosed Endometrial Cancer After Surgery With Curative Intent (MK-3475-B21 / KEYNOTE-B21 / ENGOT-en11 / GOG-3053)

Endometrial Neoplasms

2Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

  • 5 insiders sold shares within a month

    Since Aug 13, 2026 · was worth 5, fading over time

    +1.9
Worry score2

Score over time

Stage
Phase 3
Patients
990 (planned)
Started
Jan 10, 2021
Main results expected
Nov 20, 2026
Fully finished
Nov 20, 2026
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Disease-Free Survival (DFS) as Assessed Radiographically by Investigator or by Histopathologic Confirmation of Suspected Disease Recurrence

    Measured over: Up to approximately 42 months

  • Overall Survival (OS)

    Measured over: Up to approximately 54 months

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • insider_selling_cluster: base 5, now 1.9, since 2026-08-13, fades (half-life)

Raw record changes

  • none yet

Trial ID NCT04634877 · record last updated 2026-09-18 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT04634877) ↗