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MRKMerck Sharp & Dohme LLCFinished

Study of Chemoradiotherapy With or Without Pembrolizumab (MK-3475) For The Treatment of Locally Advanced Cervical Cancer (MK-3475-A18/KEYNOTE-A18/ENGOT-cx11/GOG-3047)

Uterine Cervical Neoplasms

2Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

  • 5 insiders sold shares within a month

    Since Aug 13, 2026 · was worth 5, fading over time

    +1.9
Worry score2

Score over time

Stage
Phase 3
Patients
1,060 (final count)
Started
May 12, 2020
Main results expected
Jan 7, 2025
Fully finished
Jan 26, 2026
Results posted
Jan 5, 2026

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Progression-Free Survival (PFS) Per Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST 1.1) as Assessed by the Investigator

    Measured over: Up to approximately 55 months

  • Overall Survival (OS)

    Measured over: Up to approximately 55 months

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • insider_selling_cluster: base 5, now 1.9, since 2026-08-13, fades (half-life)

Raw record changes

  • none yet

Trial ID NCT04221945 · record last updated 2026-11-05 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT04221945) ↗