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MRKMerck Sharp & Dohme LLCRunning, no new patients

Safety and Efficacy of Pembrolizumab Compared to Placebo in Resected High-risk Stage II Melanoma (MK-3475-716/KEYNOTE-716)

Melanoma

2Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

  • 5 insiders sold shares within a month

    Since Aug 13, 2026 · was worth 5, fading over time

    +1.9
Worry score2

Score over time

Stage
Phase 3
Patients
976 (final count)
Started
Sep 12, 2018
Main results expected
Jun 21, 2021
Fully finished
Oct 12, 2033
Results posted
Jun 24, 2022

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Recurrence-free Survival (RFS)

    Measured over: Up to ~32.7 months

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • insider_selling_cluster: base 5, now 1.9, since 2026-08-13, fades (half-life)

Raw record changes

  • none yet

Trial ID NCT03553836 · record last updated 2024-11-29 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT03553836) ↗