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REGNRegeneron PharmaceuticalsNot started yet

Safety and Efficacy Study in Adults With Advanced Solid Tumors Receiving REGN13089-M404-M2980, an Antibody-drug Conjugate That Targets MET Protein on Tumors

Advanced Solid Tumors

5Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

  • 5 insiders sold shares within a month

    Since Nov 4, 2026 · was worth 5, fading over time

    +4.8
Worry score5

Score over time

Stage
Phase 1/2
Patients
320 (planned)
Started
Nov 23, 2026
Main results expected
Mar 10, 2031
Fully finished
Mar 10, 2031
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Occurrence of dose-limiting toxicities (DLTs)

    Measured over: Up to 21 days

  • Occurrence of Treatment Emergent Adverse Events (TEAEs)

    Measured over: Up to approximately 5 years

  • Occurrence of Serious Adverse Events (SAEs)

    Measured over: Up to approximately 5 years

  • Occurrence of adverse event of special interests (AESIs)

    Measured over: Up to approximately 5 years

  • Objective response (OR) (investigator assessed) per Response Evaluation Criteria In Solid Tumors (RECIST) 1.1

    Measured over: Up to approximately 5 years

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • insider_selling_cluster: base 5, now 4.8, since 2026-11-04, fades (half-life)

Raw record changes

  • none yet

Trial ID NCT07863024 · record last updated 2026-10-07 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT07863024) ↗