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RVMDRevolution Medicines, Inc.Signing up patients

Study of Zoldonrasib (RMC-9805) Plus Daraxonrasib (RMC-6236) Versus Gemcitabine and Nab-Paclitaxel as First-Line Treatment in Metastatic KRAS G12D-Mutated Pancreatic Adenocarcinoma

Pancreatic Cancer · Pancreatic Cancer Metastatic · PDAC · PDAC - Pancreatic Ductal Adenocarcinoma · Pancreatic Ductal Adenocarcinoma (PDAC) · Pancreatic Adenocarcinoma Metastatic · Pancreatic Adenocarcinoma · Pancreatic Adenosquamous Carcinoma

0Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

No warning signs right now. That's why the score is 0.

Score over time

Stage
Phase 3
Patients
400 (planned)
Started
Aug 28, 2026
Main results expected
Mar 2029
Fully finished
Apr 2030
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Progression free survival (PFS)

    Measured over: Up to approximately 4 years

  • Overall survival (OS)

    Measured over: Up to approximately 4 years

Changes Tremor has spotted

  • Paperwork edit (contacts, locations, wording). Usually harmless.

    Spotted on Nov 6, 2026

Show details (technical version)

Score inputs

  • none

Raw record changes

  • 2026-11-06 15:29 UTC · paperwork · other
    old: null
    new: null
    details: {"sections":["contactsLocationsModule","statusModule"]}

Trial ID NCT07805954 · record last updated 2026-11-06 · checked 2026-11-09 15:36 UTC

See the official record on ClinicalTrials.gov (NCT07805954) ↗