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Tremor shows what changed in public records. It never tells anyone to buy or sell. Many trial edits are harmless paperwork. Data from ClinicalTrials.gov, the SEC, and the Federal Register.

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AMGNAmgenSigning up patients

Phase 3 Trial of Tarlatamab (SC vs IV) in Extensive-Stage Small Cell Lung Cancer After Platinum Based First-line Chemotherapy (ES-SCLC)

Small Cell Lung Cancer

2Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

  • 3 insiders sold shares within a month

    Since Aug 13, 2026 · was worth 5, fading over time

    +1.9
Worry score2

Score over time

Stage
Phase 3
Patients
400 (planned)
Started
Aug 28, 2026
Main results expected
Sep 24, 2027
Fully finished
Jul 30, 2030
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Area Under the Curve From Cycle 2 Day 1 to Day 15 (AUC C2D1-D15) of Tarlatamab

    Measured over: From Cycle 2 Day 1 to Day 15 (each cycle is 28 days)

  • Predose Concentration (Ctrough) of Tarlatamab

    Measured over: On Cycle 2 Day 15 (each cycle is 28 days)

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • insider_selling_cluster: base 5, now 1.9, since 2026-08-13, fades (half-life)

Raw record changes

  • none yet

Trial ID NCT07778316 · record last updated 2026-09-17 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT07778316) ↗