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ARVNArvinas Inc.Signing up patients

A Study to Evaluate ARV-6723 Alone and With Pembrolizumab in Participants With Advanced Solid Tumors

Advanced Solid Tumor

1Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

  • 5 insiders sold shares within a month

    Since May 21, 2026 · was worth 10, fading over time

    +1.4
Worry score1

Score over time

Stage
Phase 1/2
Patients
499 (planned)
Started
Jul 29, 2026
Main results expected
Mar 31, 2031
Fully finished
Mar 31, 2032
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Part A1: Number of Dose-Limiting Toxicities (DLTs) of ARV-6723

    Measured over: 21 days from first ARV-6723 administration

  • Part A1: Number of Participants With Adverse Events (AEs)

    Measured over: From the first dose of ARV-6723 through at least 28 days after the last dose (up to approximately 4.7 years)

  • Part A2: Number of Participants With AEs

    Measured over: From the first dose of ARV-6723 through at least 28 days after the last dose (up to approximately 4.7 years)

  • Part A2: Overall Response Rate (ORR) by computed tomography/magnetic resonance imaging (CT/MRI) Using Response Evaluation Criteria in Solid Tumors, version 1.1 (RECIST 1.1) Criteria Per Investigator Assessment

    Measured over: Approximately 24 months

  • Part B: ORR by CT/MRI using RECIST v1.1 Criteria Per Investigator Assessment

    Measured over: Approximately 24 months

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • insider_selling_cluster: base 10, now 1.4, since 2026-05-21, fades (half-life)

Raw record changes

  • none yet

Trial ID NCT07749586 · record last updated 2026-10-13 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT07749586) ↗