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VSTMVerastem, Inc.Not started yet

Continued Access to Avutometinib in Combination With Defactinib in Patients With Recurrent Low-Grade Serous Ovarian Cancer (LGSOC)

Low Grade Ovarian Serous Adenocarcinoma · Ovarian Cancer

12Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

  • A key executive is leaving

    Since Oct 14, 2026 · was worth 15, fading over time

    +11.5
Worry score12

Score over time

Stage
Phase 2
Patients
2 (planned)
Started
Aug 3, 2026
Main results expected
Aug 1, 2027
Fully finished
Aug 1, 2028
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Duration of Treatment Exposure to Avutometinib in Combination With Defactinib

    Measured over: Until treatment discontinuation (approximately 20 months)

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • key_exec_departure: base 15, now 11.5, since 2026-10-14, fades (half-life) · source filing

Raw record changes

  • none yet

Trial ID NCT07747506 · record last updated 2026-08-05 · checked 2026-11-09 15:42 UTC

See the official record on ClinicalTrials.gov (NCT07747506) ↗