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Tremor shows what changed in public records. It never tells anyone to buy or sell. Many trial edits are harmless paperwork. Data from ClinicalTrials.gov, the SEC, and the Federal Register.

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ONCBeOne MedicinesSigning up patients

A Study Investigating Alternate Schedules of Tislelizumab Plus Chemotherapy in Japanese Patients With First-line Advanced ESCC

Advanced Esophageal Squamous Cell Carcinoma · Metastatic Esophageal Squamous Cell Carcinoma

2Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

  • 2 insiders sold shares within a month

    Since Aug 3, 2026 · was worth 5, fading over time

    +1.7
Worry score2

Score over time

Stage
Phase 2
Patients
30 (planned)
Started
Sep 14, 2026
Main results expected
Feb 28, 2028
Fully finished
Feb 28, 2028
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Serum Concentrations of Tislelizumab at Specified Time Points

    Measured over: Approximately 12 months

  • Number of Participants with Adverse Events (AEs) and Serious Adverse Events (SAEs)

    Measured over: Approximately 12 months

  • Overall Response Rate (ORR)Assessed by Independent Review Committee (IRC)

    Measured over: Approximately 12 months

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • insider_selling_cluster: base 5, now 1.7, since 2026-08-03, fades (half-life)

Raw record changes

  • none yet

Trial ID NCT07733180 · record last updated 2026-10-26 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT07733180) ↗