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VSTMVerastem, Inc.Signing up patients

A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer

12Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

  • A key executive is leaving

    Since Oct 14, 2026 · was worth 15, fading over time

    +11.5
Worry score12

Score over time

Stage
Phase 2
Patients
105 (planned)
Started
Jul 22, 2026
Main results expected
Jun 2027
Fully finished
Dec 2028
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Confirmed ORR by blinded independent central review (BICR) per RESIST v1.1

    Measured over: 6 months

  • To characterize the safety and tolerability of VS-7375 monotherapy administered on a daily oral schedule in participants with KRAS G12D-mutated NSCLC

    Measured over: 6 months

Changes Tremor has spotted

  • Paperwork edit (contacts, locations, wording). Usually harmless.

    Spotted on Nov 6, 2026

Show details (technical version)

Score inputs

  • key_exec_departure: base 15, now 11.5, since 2026-10-14, fades (half-life) · source filing

Raw record changes

  • 2026-11-06 15:29 UTC · paperwork · other
    old: null
    new: null
    details: {"sections":["contactsLocationsModule","statusModule"]}

Trial ID NCT07659782 · record last updated 2026-11-06 · checked 2026-11-09 15:36 UTC

See the official record on ClinicalTrials.gov (NCT07659782) ↗