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HCMHutchmedSigning up patients

HMPL-A580 in Participants With Advanced or Metastatic Solid Tumor

Solid Tumors, Adult

0Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

No warning signs right now. That's why the score is 0.

Score over time

Stage
Phase 1/2
Patients
186 (planned)
Started
Mar 4, 2026
Main results expected
Dec 31, 2028
Fully finished
Jan 30, 2029
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Maximum Tolerated Dose (MTD) and/or recommended dose(s) for expansion(RDE)

    Measured over: Approximately 12 months

  • Overview of Treatment-emergent Adverse Events (TEAEs)

    Measured over: Approximately 12 months

  • Objective Response Rate (ORR)

    Measured over: At least 8 weeks post dose of first participant up to approximately 24 months

  • Recommended doses for phase II or III studies (RP2D or RP3D) of HMPL-A580

    Measured over: Approximately 12 months

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • none

Raw record changes

  • none yet

Trial ID NCT07396584 · record last updated 2026-09-18 · checked 2026-11-09 15:42 UTC

See the official record on ClinicalTrials.gov (NCT07396584) ↗