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PFEPfizerSigning up patients

Symbiotic-GI-16: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Gastroesophageal Cancer

Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction , or Esophageal Adenocarcinoma · Metastatic Gastric Cancer · Gastroesophageal Junction Cancer · Esophageal Adenocarcinoma

0Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

No warning signs right now. That's why the score is 0.

Score over time

Stage
Phase 2/3
Patients
840 (planned)
Started
May 14, 2026
Main results expected
Jul 22, 2031
Fully finished
Jul 21, 2032
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Phase 2: Confirmed Objective response rate (ORR) using RECIST 1.1 as assessed by investigator

    Measured over: Approximately 4 years

  • Phase 2: Number of participants with treatment-emergent adverse events

    Measured over: Through 90 days after the last study intervention; Approximately 4 years

  • Phase 3: Progression Free Survival (PFS) using RECIST 1.1 as assessed by BICR

    Measured over: Approximately 4 years

  • Phase 3: Overall Survival (OS)

    Measured over: Approximately 4 years

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • none

Raw record changes

  • none yet

Trial ID NCT07392892 · record last updated 2026-10-13 · checked 2026-11-09 15:42 UTC

See the official record on ClinicalTrials.gov (NCT07392892) ↗