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ONCBeOne MedicinesSigning up patients

A Study to Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Acalabrutinib in Adults With Previously Untreated Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia

2Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

  • 2 insiders sold shares within a month

    Since Aug 3, 2026 · was worth 5, fading over time

    +1.7
Worry score2

Score over time

Stage
Phase 3
Patients
500 (planned)
Started
Jan 22, 2026
Main results expected
Feb 2031
Fully finished
Nov 2031
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Progression-Free Survival (PFS) as Determined by Independent Review Committee (IRC)

    Measured over: Up to approximately 70 months

  • Rate of Undetectable Minimal Residual Disease at < 10^-4 sensitivity (uMRD4)

    Measured over: Up to approximately 16 months

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • insider_selling_cluster: base 5, now 1.7, since 2026-08-03, fades (half-life)

Raw record changes

  • none yet

Trial ID NCT07277231 · record last updated 2026-09-28 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT07277231) ↗