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REGNRegeneron PharmaceuticalsSigning up patients

A Study to Compare Linvoseltamab Monotherapy and Linvoseltamab + Carfilzomib Combination Therapy With Standard-of-Care Combination Regimens in Adult Participants With Relapsed/Refractory Multiple Myeloma (RRMM)

Relapsed and/or Refractory Multiple Myeloma (RRMM)

5Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

  • 5 insiders sold shares within a month

    Since Nov 4, 2026 · was worth 5, fading over time

    +4.8
Worry score5

Score over time

Stage
Phase 3
Patients
915 (planned)
Started
Jan 2, 2026
Main results expected
May 21, 2029
Fully finished
Aug 23, 2034
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Occurrence of Treatment Emergent Adverse Events (TEAEs)

    Measured over: Up to 5 years

  • Severity of TEAEs

    Measured over: Up to 5 years

  • Occurrence of Adverse Events of Special Interest (AESI)

    Measured over: Up to 5 years

  • Severity of AESIs

    Measured over: Up to 5 years

  • Occurrence of Serious Adverse Events (SAEs)

    Measured over: Up to 5 years

  • Severity of SAEs

    Measured over: Up to 5 years

  • Minimal Residual Disease (MRD)-negative Complete Response (CR)

    Measured over: At 12 months

  • Progression-Free Survival (PFS) per IMWG response criteria as determined by BIRC

    Measured over: Up to 5 years

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • insider_selling_cluster: base 5, now 4.8, since 2026-11-04, fades (half-life)

Raw record changes

  • none yet

Trial ID NCT07222761 · record last updated 2026-11-04 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT07222761) ↗