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LLYEli Lilly and CompanySigning up patients

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

Carcinoma, Transitional Cell · Urinary Bladder Neoplasms · Neoplasm Metastasis

0Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

No warning signs right now. That's why the score is 0.

Score over time

Stage
Phase 3
Patients
450 (planned)
Started
Dec 12, 2025
Main results expected
Oct 2029
Fully finished
May 2033
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Number of participants with treatment-related adverse events related to vepugratinib in combination with EV and pembrolizumab

    Measured over: From baseline up to 90 months

  • Safety Lead-in: Overall Response Rate (ORR)

    Measured over: From baseline up to 90 months

  • Progression-free Survival (PFS)

    Measured over: Baseline to Study Completion (estimated as 6 years)

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • none

Raw record changes

  • none yet

Trial ID NCT07218380 · record last updated 2026-10-07 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT07218380) ↗