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IDYAIDEAYA BiosciencesSigning up patients

A Study of IDE849 in Patients With DLL3 Expressing Tumors Including Small Cell Lung Cancer

Small-cell Lung Cancer · Neuroendocrine Carcinomas · Solid Tumor Show to Express DLL3

0Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

No warning signs right now. That's why the score is 0.

Score over time

Stage
Phase 1/2
Patients
262 (planned)
Started
Oct 14, 2025
Main results expected
Jul 2029
Fully finished
Jul 2029
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Part 1A: Safety and Tolerability of IDE849 (Monotherapy)

    Measured over: approximately 4 years total study duration

  • Part 1B: Safety and Tolerability of IDE849 in Combination with durvalumab or IDE161

    Measured over: approximately 4 years total study duration

  • Part 2: Safety and Tolerability of IDE849 (Monotherapy Dose Expansion)

    Measured over: approximately 4 years total study duration

  • Part 2: Safety and Tolerability of IDE849 in Combination with durvalumab or IDE161 or durvalumab + carboplatin (Dose Expansion)

    Measured over: approximately 4 years total study duration

  • Part 2: Objective Response Rate (ORR) and Investigator Assessment of IDE849 ORR per RECIST 1.1

    Measured over: approximately 4 years total study duration

  • Part 2: Duration of Response (DOR) and Investigator Assessment of IDE849 DOR per RECIST 1.1

    Measured over: approximately 4 years total study duration

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • none

Raw record changes

  • none yet

Trial ID NCT07174583 · record last updated 2026-07-09 · checked 2026-11-09 15:36 UTC

See the official record on ClinicalTrials.gov (NCT07174583) ↗