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BMYBristol-Myers SquibbSigning up patients

Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)

Non-Small Cell Lung Cancer

3Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

  • 2 insiders sold shares within a month

    Since Sep 9, 2026 · was worth 5, fading over time

    +2.6
Worry score3

Score over time

Stage
Phase 2/3
Patients
500 (planned)
Started
Nov 5, 2025
Main results expected
Dec 15, 2028
Fully finished
Nov 15, 2030
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Recommended Phase 3 Dose (RP3D) of BMS-986507

    Measured over: Approximately 3 months after the first dose

  • Progression-Free Survival (PFS) Assessed by Response Evaluation Criteria in Solid Tumors version 1.1 (RECIST v1.1) per blinded independent central review (BICR)

    Measured over: Up to 3 years

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • insider_selling_cluster: base 5, now 2.6, since 2026-09-09, fades (half-life)

Raw record changes

  • none yet

Trial ID NCT07100080 · record last updated 2026-10-09 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT07100080) ↗