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ARVNArvinas Inc.Running, no new patients

A Study to Evaluate ARV-806 in Adults With Advanced Cancer That Has the KRAS G12D Mutation

KRAS G12D Mutation · Advanced Solid Cancer

1Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

  • 5 insiders sold shares within a month

    Since May 21, 2026 · was worth 10, fading over time

    +1.4
Worry score1

Score over time

Stage
Phase 1/2
Patients
76 (final count)
Started
May 29, 2025
Main results expected
Nov 30, 2026
Fully finished
Nov 30, 2026
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Part A (Phase 1): Number of dose-limiting toxicities (DLTs) of ARV-806

    Measured over: 28 days from first ARV-806 administration

  • Part A (Phase 1): Number of participants with AEs

    Measured over: From the study baseline to at least 28 days after last dose of ARV-806

  • Part B (Phase 2): Overall Response Rate (ORR)

    Measured over: Approximately 2 years

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • insider_selling_cluster: base 10, now 1.4, since 2026-05-21, fades (half-life)

Raw record changes

  • none yet

Trial ID NCT07023731 · record last updated 2026-09-16 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT07023731) ↗