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ABBVAbbVieSigning up patients

A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Multiple Myeloma Receiving T Cell Engaging Bi/Tri-specific Antibodies Intravenously (IV)/Subcutaneously (SC) Alone or in Combinations

Multiple Myeloma

0Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

No warning signs right now. That's why the score is 0.

Score over time

Stage
Phase 1/2
Patients
602 (planned)
Started
Jun 30, 2025
Main results expected
Dec 2035
Fully finished
Mar 2036
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Number of Participants with Adverse Events (AE)s

    Measured over: Up to Approximately 130 Months

  • Substudy 1: Dose-Limiting Toxicity (DLT) of Etentamig + Daratumumab and Lenalidomide (DR) in Participants with Transplant-Ineligible Newly Diagnosed Multiple Myeloma (TI NDMM)

    Measured over: Up to Approximately 8 weeks

  • Substudy 2: DLT of Etentamig Monotherapy as Maintenance in Participants with Transplant-Eligible Newly Diagnosed Multiple Myeloma (TE NDMM)

    Measured over: Up to Approximately 8 Weeks

  • Substudy 3: DLT of Etentamig +Carfilzomib and Dexamethasone (Kd) Combination in Participants with Relapsed or Refractory Multiple Myeloma (RR MM)

    Measured over: Up to Approximately 8 Weeks

  • Substudy 4: DLT of Etentamig plus Lenalidomide when Given as Maintenance in Participants with TE NDMM

    Measured over: Up to Approximately 8 Weeks

  • Substudy 5: DLT of ABBV-2001 in Combination with Iberdomide in Participants with RR MM

    Measured over: Up to Approximately 8 Weeks

  • Substudy 6: DLT of ABBV-2001 in Combination with Mezigdomide in Participants with RR MM

    Measured over: Up to Approximately 8 Weeks

  • Substudy 7: DLT of ABBV-2001 in Combination with Pomalidomide in Participants with RR MM

    Measured over: Up to Approximately 8 Weeks

  • Substudy 8: DLT of ABBV-2001 in Combination with Lenalidomide in Participants with RR MM

    Measured over: Up to Approximately 8 Weeks

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • none

Raw record changes

  • none yet

Trial ID NCT06892522 · record last updated 2026-10-19 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT06892522) ↗