A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Multiple Myeloma Receiving T Cell Engaging Bi/Tri-specific Antibodies Intravenously (IV)/Subcutaneously (SC) Alone or in Combinations
Multiple Myeloma
No strong warning signs right now. The score counts warning signs; it is not a prediction.
Why this score
No warning signs right now. That's why the score is 0.
Score over time
- Stage
- Phase 1/2
- Patients
- 602 (planned)
- Started
- Jun 30, 2025
- Main results expected
- Dec 2035
- Fully finished
- Mar 2036
- Results posted
- not yet
What counts as success
The trial's main goal(s), called the “primary outcome.”
Number of Participants with Adverse Events (AE)s
Measured over: Up to Approximately 130 Months
Substudy 1: Dose-Limiting Toxicity (DLT) of Etentamig + Daratumumab and Lenalidomide (DR) in Participants with Transplant-Ineligible Newly Diagnosed Multiple Myeloma (TI NDMM)
Measured over: Up to Approximately 8 weeks
Substudy 2: DLT of Etentamig Monotherapy as Maintenance in Participants with Transplant-Eligible Newly Diagnosed Multiple Myeloma (TE NDMM)
Measured over: Up to Approximately 8 Weeks
Substudy 3: DLT of Etentamig +Carfilzomib and Dexamethasone (Kd) Combination in Participants with Relapsed or Refractory Multiple Myeloma (RR MM)
Measured over: Up to Approximately 8 Weeks
Substudy 4: DLT of Etentamig plus Lenalidomide when Given as Maintenance in Participants with TE NDMM
Measured over: Up to Approximately 8 Weeks
Substudy 5: DLT of ABBV-2001 in Combination with Iberdomide in Participants with RR MM
Measured over: Up to Approximately 8 Weeks
Substudy 6: DLT of ABBV-2001 in Combination with Mezigdomide in Participants with RR MM
Measured over: Up to Approximately 8 Weeks
Substudy 7: DLT of ABBV-2001 in Combination with Pomalidomide in Participants with RR MM
Measured over: Up to Approximately 8 Weeks
Substudy 8: DLT of ABBV-2001 in Combination with Lenalidomide in Participants with RR MM
Measured over: Up to Approximately 8 Weeks
Changes Tremor has spotted
Show details (technical version)
Score inputs
- none
Raw record changes
- none yet
Trial ID NCT06892522 · record last updated 2026-10-19 · checked 2026-11-09 15:47 UTC