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BMYMirati Therapeutics Inc.Signing up patients

A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)

Carcinoma, Non-Small-Cell Lung

3Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

  • 2 insiders sold shares within a month

    Since Sep 9, 2026 · was worth 5, fading over time

    +2.6
Worry score3

Score over time

Stage
Phase 3
Patients
630 (planned)
Started
Apr 24, 2025
Main results expected
Sep 7, 2029
Fully finished
Apr 30, 2032
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Progression Free Survival (PFS) as Assessed per Response Evaluation Criteria in Solid Tumors (RECIST) v1.1 by Blinded Independent Central Review (BICR)

    Measured over: Up to 7 years

  • Overall Survival (OS)

    Measured over: Up to 7 years

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • insider_selling_cluster: base 5, now 2.6, since 2026-09-09, fades (half-life)

Raw record changes

  • none yet

Trial ID NCT06875310 · record last updated 2026-10-27 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT06875310) ↗