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TNGXTango Therapeutics, Inc.Signing up patients

Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

Non Small Cell Lung Cancer · Glioma Glioblastoma Multiforme · Glioma, Malignant · Solid Tumor · Non-Small Cell Adenocarcinoma · Lung Cancer · Brain Tumor

0Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

No warning signs right now. That's why the score is 0.

Score over time

Stage
Phase 1/2
Patients
191 (planned)
Started
Mar 24, 2025
Main results expected
Mar 31, 2027
Fully finished
Sep 30, 2027
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Phase 1 Maximum Tolerated Dose

    Measured over: 21 days

  • Phase 2 Anti-neoplastic Activity Single Agent

    Measured over: 18 weeks

  • Phase 2 Anti-neoplastic Activity Combination Treatment

    Measured over: 18 weeks

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • none

Raw record changes

  • none yet

Trial ID NCT06810544 · record last updated 2026-10-21 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT06810544) ↗