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VSTMVerastem, Inc.Running, no new patients

A Study of Avutometinib + Defactinib in Recurrent Low-Grade Serous Ovarian Cancer in Japanese Patients

Low Grade Serous Ovarian Cancer · Ovarian Cancer

12Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

  • A key executive is leaving

    Since Oct 14, 2026 · was worth 15, fading over time

    +11.5
Worry score12

Score over time

Stage
Phase 2
Patients
16 (final count)
Started
Oct 30, 2024
Main results expected
Dec 2025
Fully finished
Oct 2027
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Confirmed overall response rate (ORR; partial response [PR] + complete response [CR]

    Measured over: From start of treatment to confirmation of response; 24 weeks

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • key_exec_departure: base 15, now 11.5, since 2026-10-14, fades (half-life) · source filing

Raw record changes

  • none yet

Trial ID NCT06682572 · record last updated 2025-12-17 · checked 2026-11-09 15:42 UTC

See the official record on ClinicalTrials.gov (NCT06682572) ↗