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ACRVAcrivon TherapeuticsSigning up patients

Study of ACR-2316 in Specific Advanced Solid Tumors

Specific Advanced Solid Tumors

4Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

  • 6 insiders sold shares within a month

    Since Aug 18, 2026 · was worth 10, fading over time

    +4
Worry score4

Score over time

Stage
Phase 1/2
Patients
100 (planned)
Started
Oct 8, 2024
Main results expected
Aug 12, 2027
Fully finished
Dec 12, 2027
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Dose Escalation

    Measured over: Number of DLT events during the DLT observation period (up to 28 days)

  • Dose Expansion

    Measured over: RP2D supported by safety, PK and PD data through study completion

  • Dose Expansion

    Measured over: Incidence and grades of TEAEs and TRAEs per NCI CTCAE v.5.0 and number of dose decreases, number of dose delays, and SAEs through study completion, an average of 1 year.

  • Dose Expansion

    Measured over: Confirmed ORR per Recist v1.1 and DOR, CBR, assessed every 6 weeks from baseline thorough study completion, an average 1 year or until death.

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • insider_selling_cluster: base 10, now 4, since 2026-08-18, fades (half-life)

Raw record changes

  • none yet

Trial ID NCT06667141 · record last updated 2026-09-23 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT06667141) ↗