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REGNRegeneron PharmaceuticalsRunning, no new patients

A Study of Cemiplimab Plus Chemotherapy Versus Cemiplimab Plus Chemotherapy Plus Other Cancer Treatments for Adult Patients With Operable Non-Small Cell Lung Cancer (NSCLC)

Non Small Cell Lung Cancer · NSCLC

5Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

  • 5 insiders sold shares within a month

    Since Nov 4, 2026 · was worth 5, fading over time

    +4.8
Worry score5

Score over time

Stage
Phase 2
Patients
184 (planned)
Started
Nov 18, 2024
Main results expected
Dec 4, 2029
Fully finished
Dec 27, 2034
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Major Pathologic Response (MPR) rate as determined by central Blinded Independent Pathology Review (BIPR)

    Measured over: Up to 12 weeks

  • Occurrence of Treatment-Emergent Adverse Events (TEAEs)

    Measured over: Up to 9 weeks

  • Occurrence of TEAEs leading to death

    Measured over: Up to 9 weeks

  • Occurrence of TEAEs leading to treatment discontinuation

    Measured over: Up to 9 weeks

  • Occurrence of Serious Adverse Events (SAEs)

    Measured over: Up to 9 weeks

  • Occurrence of grade ≥3 laboratory abnormalities

    Measured over: Up to 9 weeks

  • Number of participants unable to receive cemiplimab and chemotherapy for 2 consecutive cycles due to REGN10597-related toxicities during the first 3 cycles

    Measured over: Up to 9 weeks

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • insider_selling_cluster: base 5, now 4.8, since 2026-11-04, fades (half-life)

Raw record changes

  • none yet

Trial ID NCT06465329 · record last updated 2026-11-03 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT06465329) ↗