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Tremor shows what changed in public records. It never tells anyone to buy or sell. Many trial edits are harmless paperwork. Data from ClinicalTrials.gov, the SEC, and the Federal Register.

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JAZZJazz PharmaceuticalsSigning up patients

A Study Comparing the Efficacy and Safety of Zanidatamab to Trastuzumab, Each in Combination With Physician's Choice Chemotherapy, for the Treatment of Participants With Metastatic HER2-positive Breast Cancer

Metastatic HER2-positive Breast Cancer

2Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

  • 3 insiders sold shares within a month

    Since May 28, 2026 · was worth 10, fading over time

    +1.5
Worry score2

Score over time

Stage
Phase 3
Patients
550 (planned)
Started
Aug 13, 2024
Main results expected
Apr 28, 2028
Fully finished
Oct 18, 2030
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Progression-free Survival (PFS) Per RECIST Version 1.1 As Assessed by Blinded Independent Central Review (BICR)

    Measured over: Until disease progression or death, up to approximately 44 months

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • insider_selling_cluster: base 10, now 1.5, since 2026-05-28, fades (half-life)

Raw record changes

  • none yet

Trial ID NCT06435429 · record last updated 2026-02-10 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT06435429) ↗