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REPLReplimune, Inc.Signing up patients

VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs [IGNYTE-3]

Advanced Melanoma

4Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

  • 4 insiders sold shares within a month

    Since Aug 17, 2026 · was worth 10, fading over time

    +3.9
Worry score4

Score over time

Stage
Phase 3
Patients
400 (planned)
Started
Jul 11, 2024
Main results expected
Sep 30, 2030
Fully finished
Mar 31, 2031
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Overall Survival (OS)

    Measured over: Assessed up to January 2029, approximately 55 months

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • insider_selling_cluster: base 10, now 3.9, since 2026-08-17, fades (half-life)

Raw record changes

  • none yet

Trial ID NCT06264180 · record last updated 2026-07-15 · checked 2026-11-09 15:36 UTC

See the official record on ClinicalTrials.gov (NCT06264180) ↗