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RVMDRevolution Medicines, Inc.Signing up patients

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

Non-Small Cell Lung Cancer (NSCLC) · Colorectal Cancer · Pancreatic Ductal Adenocarcinoma

0Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

No warning signs right now. That's why the score is 0.

Score over time

Stage
Phase 1/2
Patients
534 (planned)
Started
Nov 14, 2023
Main results expected
Dec 2028
Fully finished
Jun 2029
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Number of patients with adverse events (AEs) in Phase 1b

    Measured over: Up to approximately 3 years

  • Changes in vital signs in Phase 1b

    Measured over: Up to approximately 3 years

  • Changes in clinical laboratory test values in Phase 1b

    Measured over: Up to approximately 3 years

  • Dose Limiting Toxicities in Phase 1b

    Measured over: 21 days

  • Changes in ECGs in Phase 1b

    Measured over: Up to approximately 3 years

  • Overall Response Rate (ORR) in Phase 2

    Measured over: Up to approximately 3 years

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • none

Raw record changes

  • none yet

Trial ID NCT06128551 · record last updated 2026-09-22 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT06128551) ↗