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REGNRegeneron PharmaceuticalsSigning up patients

A Study to Compare How Well Odronextamab Combined With Chemotherapy Works and How Safe it is Against Rituximab Combined With Chemotherapy, in Adult Patients With Previously Untreated Diffuse Large B-cell Lymphoma

Diffuse Large B-cell Lymphoma (DLBCL)

5Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

  • 5 insiders sold shares within a month

    Since Nov 4, 2026 · was worth 5, fading over time

    +4.8
Worry score5

Score over time

Stage
Phase 3
Patients
904 (planned)
Started
Dec 13, 2023
Main results expected
Mar 30, 2028
Fully finished
Sep 12, 2029
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Incidence of Dose Limiting Toxicities (DLTs)

    Measured over: Up to 35 days

  • Incidence of Treatment Emergent Adverse Events (TEAEs)

    Measured over: Up to 2 years

  • Severity of TEAEs

    Measured over: Up to 2 years

  • Progression Free Survival (PFS), assessed by Independent Central Review (ICR)

    Measured over: Up to 5 years

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • insider_selling_cluster: base 5, now 4.8, since 2026-11-04, fades (half-life)

Raw record changes

  • none yet

Trial ID NCT06091865 · record last updated 2026-11-04 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT06091865) ↗