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LYELLyell Immunopharma, Inc.Signing up patients

Study of Rondecabtagene Autoleucel in Aggressive Large B-Cell Lymphoma

Relapsed Non-Hodgkin Lymphoma · Refractory Non-Hodgkin Lymphoma · Non-Hodgkin Lymphoma · Large B-cell Lymphoma

4Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

  • 4 insiders sold shares within a month

    Since Aug 21, 2026 · was worth 10, fading over time

    +4.1
Worry score4

Score over time

Stage
Phase 1/2
Patients
270 (planned)
Started
May 9, 2023
Main results expected
Dec 31, 2028
Fully finished
Jun 30, 2031
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Phase 1: Evaluate the safety and tolerability of a single dose of ronde-cel administered as a single agent

    Measured over: Baseline to Month 24

  • Phase 2: Estimate the efficacy of ronde-cel, as measured by overall response rate (ORR)

    Measured over: Baseline to Month 24

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • insider_selling_cluster: base 10, now 4.1, since 2026-08-21, fades (half-life)

Raw record changes

  • none yet

Trial ID NCT05826535 · record last updated 2026-08-25 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT05826535) ↗