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AZNAstraZenecaRunning, no new patients

Phase III, Open-label, First-line Study of Dato-DXd in Combination With Durvalumab and Carboplatin for Advanced NSCLC Without Actionable Genomic Alterations

NSCLC

0Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

No warning signs right now. That's why the score is 0.

Score over time

Stage
Phase 3
Patients
1,350 (final count)
Started
Dec 29, 2022
Main results expected
Nov 1, 2027
Fully finished
Nov 1, 2027
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Progression-Free Survival (PFS) by blinded independent central review (BICR) in the non-squamous TROP2 biomarker positive population

    Measured over: Approximately 3 years

  • Overall Survival (OS) in the non-squamous TROP2 biomarker positive population

    Measured over: Approximately 5 years

  • PFS by BICR in the non-squamous population

    Measured over: Approximately 3 years

  • OS in the non-squamous population

    Measured over: Approximately 5 years

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • none

Raw record changes

  • none yet

Trial ID NCT05687266 · record last updated 2026-10-09 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT05687266) ↗