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CRSPCRISPR Therapeutics AGSigning up patients

A Safety and Efficacy Study Evaluating CTX112 in Subjects With Relapsed or Refractory B-Cell Malignancies

B-cell Lymphoma · Non-Hodgkin Lymphoma · B-cell Malignancy · Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL) · Follicular Lymphoma · Mantle Cell Lymphoma · Marginal Zone Lymphoma · Large B-cell Lymphoma

8Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

  • 3 insiders sold shares within a month

    Since Oct 14, 2026 · was worth 10, fading over time

    +7.7
Worry score8

Score over time

Stage
Phase 1/2
Patients
120 (planned)
Started
Mar 10, 2023
Main results expected
Jan 2030
Fully finished
Feb 2030
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Phase 1 (Dose Escalation): Incidence of adverse events, defined as dose-limiting toxicities

    Measured over: From CTX112 infusion up to 28 days post-infusion

  • Phase 2 (Cohort Expansion): Objective response rate

    Measured over: From CTX112 infusion up to 60 months post-infusion

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • insider_selling_cluster: base 10, now 7.7, since 2026-10-14, fades (half-life)

Raw record changes

  • none yet

Trial ID NCT05643742 · record last updated 2025-11-14 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT05643742) ↗