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Tremor shows what changed in public records. It never tells anyone to buy or sell. Many trial edits are harmless paperwork. Data from ClinicalTrials.gov, the SEC, and the Federal Register.

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JNJJanssen Research & Development, LLCSigning up patients

A Study of Amivantamab in Participants With Advanced or Metastatic Solid Tumors Including Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer

Carcinoma, Non-small-Cell Lung

2Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

  • 4 insiders sold shares within a month

    Since Aug 17, 2026 · was worth 5, fading over time

    +2
Worry score2

Score over time

Stage
Phase 2
Patients
520 (planned)
Started
Nov 11, 2022
Main results expected
Aug 17, 2027
Fully finished
Aug 18, 2028
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • All Cohorts Except Cohort 4: Objective Response Rate (ORR) Based on Investigator Assessment (INV)

    Measured over: Up to 1 year 6 months

  • Cohort 4: Number of Participants with Adverse Events (AEs)

    Measured over: Up to approximately 4 years and 9 months

  • Cohort 4: Number of Participants with AEs by Severity

    Measured over: Up to approximately 4 years and 9 months

  • Cohort 4: Number of Participants with Abnormalities in Clinical Laboratory Values

    Measured over: Up to approximately 4 years and 9 months

  • Cohort 4: Number of Participants with Abnormalities in Clinical Laboratory Values by Severity

    Measured over: Up to approximately 4 years and 9 months

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • insider_selling_cluster: base 5, now 2, since 2026-08-17, fades (half-life)

Raw record changes

  • none yet

Trial ID NCT05498428 · record last updated 2026-11-03 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT05498428) ↗