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AZNAstraZenecaSigning up patients

Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)

Endometrial Cancer · Gastric Cancer · Metastatic Castration-resistant Prostate Cancer · Ovarian Cancer · Colorectal Cancer · Urothelial Cancer · Biliary Tract Cancer

0Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

No warning signs right now. That's why the score is 0.

Score over time

Stage
Phase 2
Patients
454 (planned)
Started
Sep 6, 2022
Main results expected
Oct 1, 2027
Fully finished
Oct 1, 2027
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Objective response rate (ORR)

    Measured over: From baseline to progressive disease or death (approximately 1 year)

  • The number of subjects with adverse events/serious adverse events

    Measured over: Throughout the treatment and the safety follow-up period 28 [+ 7] days after the discontinuation of all study interventions, except durvalumab, nivolumab, and bevacizumab for which it will be 90 [+ 7] days (approximately 1 year)

  • PSA50 response (Substudy 3 only)

    Measured over: From baseline to PSA response evaluated according to the PCWG3 criteria (approximately 1 year)

  • Progression free survival (PFS) response (Substudy 4C only)

    Measured over: From baseline to progressive disease or death (approximately 1 year)

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • none

Raw record changes

  • none yet

Trial ID NCT05489211 · record last updated 2026-09-23 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT05489211) ↗