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ADG126 in Combination With Pembrolizumab in Patients With Advanced/Metastatic Solid Tumors

Advanced/Metastatic Solid Tumors

0Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

No warning signs right now. That's why the score is 0.

Score over time

Stage
Phase 1/2
Patients
186 (planned)
Started
Jun 15, 2022
Main results expected
Jun 30, 2027
Fully finished
Dec 31, 2027
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Maximum tolerated dose (MTD) and RP2D for ADG126 in combination with pembrolizumab.

    Measured over: 9 months

  • the safety and tolerability of ADG126 at escalating dose level in combination with pembrolizumab in adults with advanced metastatic solid tumors

    Measured over: 9 months

  • Access the preliminary antitumor activity of ADG126-pembrolizumab combination regimens

    Measured over: 9 months

  • Maximum tolerated dose (MTD) and/or RP2D for ADG126 with Trifluridine/Tipiracil-Bevacizumab

    Measured over: 6 months

  • Access the preliminary antitumor activity of ADG126 with Pembrolizumab in combination standard of care

    Measured over: 6 months

  • Access and characterize the optimal dose based on safety and efficacy parameters

    Measured over: 9 months

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • none

Raw record changes

  • none yet

Trial ID NCT05405595 · record last updated 2026-11-02 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT05405595) ↗