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CGEMCullinan Therapeutics Inc.Signing up patients

CLN-049 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)

Relapsed/Refractory Acute Myeloid Leukemia (AML) · Myelodysplastic Syndrome (MDS) · TP53-mutated MDS and AML

0Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

No warning signs right now. That's why the score is 0.

Score over time

Stage
Phase 1/2
Patients
275 (planned)
Started
Nov 18, 2021
Main results expected
Dec 30, 2029
Fully finished
Dec 30, 2029
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Number of treatment emergent events (TEAEs)

    Measured over: 28 days

  • Cmax of CLN-049

    Measured over: Up to 13 weeks

  • Ctrough of CLN-049

    Measured over: 28 Days

  • Tmax of CLN-049

    Measured over: 28 Days

  • T1/2 of CLN-049

    Measured over: Up to 28 days

  • Efficacy of CLN-049

    Measured over: Up to 13 weeks

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • none

Raw record changes

  • none yet

Trial ID NCT05143996 · record last updated 2026-10-28 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT05143996) ↗