Tremor
TrialsCompanies

Not investment advice.

Tremor shows what changed in public records. It never tells anyone to buy or sell. Many trial edits are harmless paperwork. Data from ClinicalTrials.gov, the SEC, and the Federal Register.

PrivacyTerms

IONSIonis Pharmaceuticals, Inc.Finished

A Study to Evaluate Sapablursen (Formerly ISIS 702843, IONIS-TMPRSS6-LRx) in Patients With Polycythemia Vera

Phlebotomy Dependent Polycythemia Vera

18Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

  • Main results were due Jun 2025, none posted yet

    Counts until it's fixed

    +10
  • 2 insiders sold shares within a month

    Since Oct 16, 2026 · was worth 10, fading over time

    +7.8
Worry score18

Score over time

Stage
Phase 2
Patients
50 (final count)
Started
Dec 30, 2021
Main results expected
Jun 26, 2025
Fully finished
Jun 2, 2026
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Change in the frequency of phlebotomy comparing Baseline with the last 20 weeks of the 37 week Treatment Period

    Measured over: Week 17 to Week 37

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • results_overdue: base 10, now 10, since 2025-06-26, no fading
  • insider_selling_cluster: base 10, now 7.8, since 2026-10-16, fades (half-life)

Raw record changes

  • none yet

Trial ID NCT05143957 · record last updated 2026-07-09 · checked 2026-11-09 06:30 UTC

See the official record on ClinicalTrials.gov (NCT05143957) ↗