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Tremor shows what changed in public records. It never tells anyone to buy or sell. Many trial edits are harmless paperwork. Data from ClinicalTrials.gov, the SEC, and the Federal Register.

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PFESeagen, a wholly owned subsidiary of PfizerRunning, no new patients

A Study of Tucatinib or Placebo With Trastuzumab and Pertuzumab for Metastatic HER2+ Breast Cancer

HER2 Positive Breast Cancer

0Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

No warning signs right now. That's why the score is 0.

Score over time

Stage
Phase 3
Patients
654 (final count)
Started
Mar 7, 2022
Main results expected
Sep 5, 2025
Fully finished
Sep 28, 2027
Results posted
Sep 29, 2026

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Progression-Free Survival (PFS) as Assessed by Investigator Per Response Evaluation Criteria in Solid Tumors (RECIST) Version (v) 1.1

    Measured over: From randomization until the first documentation of PD or death from any cause or censoring date, whichever occurred first (maximum treatment exposure was of 41.3 months)

Changes Tremor has spotted

  • Paperwork edit (contacts, locations, wording). Usually harmless.

    Spotted on Nov 9, 2026

Show details (technical version)

Score inputs

  • none

Raw record changes

  • 2026-11-09 15:36 UTC · paperwork · other
    old: null
    new: null
    details: {"sections":["referencesModule"]}

Trial ID NCT05132582 · record last updated 2026-09-29 · checked 2026-11-09 15:42 UTC

See the official record on ClinicalTrials.gov (NCT05132582) ↗