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Tremor shows what changed in public records. It never tells anyone to buy or sell. Many trial edits are harmless paperwork. Data from ClinicalTrials.gov, the SEC, and the Federal Register.

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JAZZJazz PharmaceuticalsFinished

A Study of Zanidatamab (ZW25) With Evorpacept (ALX148) in Patients With Advanced HER2-expressing Cancer

HER2-expressing Cancers

12Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

  • Main results were due Aug 2025, none posted yet

    Counts until it's fixed

    +10
  • 3 insiders sold shares within a month

    Since May 28, 2026 · was worth 10, fading over time

    +1.5
Worry score12

Score over time

Stage
Phase 1/2
Patients
52 (final count)
Started
Sep 15, 2021
Main results expected
Aug 29, 2025
Fully finished
Sep 30, 2025
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Incidence of dose-limiting toxicities (DLTs; Part 1)

    Measured over: Up to 4 weeks

  • Incidence of AEs (Part 1)

    Measured over: Up to 7 months

  • Incidence of clinical laboratory abnormalities (Part 1)

    Measured over: Up to 7 months

  • Confirmed objective response rate (ORR)(Part 2)

    Measured over: Up to 2 years

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • results_overdue: base 10, now 10, since 2025-08-29, no fading
  • insider_selling_cluster: base 10, now 1.5, since 2026-05-28, fades (half-life)

Raw record changes

  • none yet

Trial ID NCT05027139 · record last updated 2026-07-01 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT05027139) ↗