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PFEPfizerRunning, no new patients

A Clinical Trial of Three Study Medicines (Encorafenib, Binimetinib, and Pembrolizumab) in Patients With Advanced or Metastatic Melanoma

Melanoma

0Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

No warning signs right now. That's why the score is 0.

Score over time

Stage
Phase 3
Patients
257 (final count)
Started
Jan 15, 2021
Main results expected
Oct 30, 2026
Fully finished
Oct 30, 2026
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Safety Lead In (SLI): Incidence of Dose Limiting Toxicities (DLTs)

    Measured over: First 2 Cycles of Treatment (cycles are 21 days)

  • Phase 3: Objective Response (OR) by Blinded Independent Central Review (BICR)

    Measured over: Time from the date of randomization until documented PD, start of subsequent anticancer therapy, or death due to any cause (approximately every 9 weeks).

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • none

Raw record changes

  • none yet

Trial ID NCT04657991 · record last updated 2026-09-03 · checked 2026-11-09 15:36 UTC

See the official record on ClinicalTrials.gov (NCT04657991) ↗