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AZNAstraZenecaRunning, no new patients

Study of AZD5305 as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Malignancies

Ovarian Cancer · Breast Cancer · Pancreatic Cancer · Prostate Cancer · Additional Indications Below for Module 4 and 5 · Non-small Cell Lung Cancer · Colorectal Cancer · Bladder Cancer · Gastric Cancer · Biliary Cancer · Cervical Cancer · Endometrial Cancer · Small Cell Lung Cancer Only in Module 5

0Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

No warning signs right now. That's why the score is 0.

Score over time

Stage
Phase 1/2
Patients
702 (final count)
Started
Nov 12, 2020
Main results expected
May 28, 2027
Fully finished
May 28, 2027
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • The number of subjects with adverse events/serious adverse events

    Measured over: From time of Informed Consent to 28 + 7 days post last dose ( modules 1,2,3,5 and 6). 40+7 days post last dose for Module 4.

  • The number of subjects with dose-limiting toxicity (DLT), as defined in the protocol.

    Measured over: From first dose of study treatment until the end of Cycle 1.

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • none

Raw record changes

  • none yet

Trial ID NCT04644068 · record last updated 2026-09-21 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT04644068) ↗