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BMYMirati Therapeutics Inc.Signing up patients

Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7

Advanced Non-Small Cell Lung Cancer · Metastatic Non-Small Cell Lung Cancer

3Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

  • 2 insiders sold shares within a month

    Since Sep 9, 2026 · was worth 5, fading over time

    +2.6
Worry score3

Score over time

Stage
Phase 2/3
Patients
626 (planned)
Started
Dec 2, 2020
Main results expected
Oct 31, 2028
Fully finished
Oct 31, 2029
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Phase 2: To evaluate the efficacy of Adagrasib monotherapy and in combination with pembrolizumab administered to patients having advanced/metastatic NSCLC.

    Measured over: 22 months

  • Phase 3: To compare efficacy of Adagrasib in combination with pembrolizumab versus pembrolizumab

    Measured over: 36 months

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • insider_selling_cluster: base 5, now 2.6, since 2026-09-09, fades (half-life)

Raw record changes

  • none yet

Trial ID NCT04613596 · record last updated 2026-10-30 · checked 2026-11-09 15:42 UTC

See the official record on ClinicalTrials.gov (NCT04613596) ↗