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JNJJanssen Research & Development, LLCRunning, no new patients

A Study of the Combination of Talquetamab and Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma

Multiple Myeloma

12Calmworry score, out of 100

No strong warning signs right now. The score counts warning signs; it is not a prediction.

Why this score

  • Main results were due Mar 2025, none posted yet

    Counts until it's fixed

    +10
  • 4 insiders sold shares within a month

    Since Aug 17, 2026 · was worth 5, fading over time

    +2
Worry score12

Score over time

Stage
Phase 1/2
Patients
228 (final count)
Started
Dec 15, 2020
Main results expected
Mar 18, 2025
Fully finished
Oct 27, 2026
Results posted
not yet

What counts as success

The trial's main goal(s), called the “primary outcome.”

  • Part 1: Number of Participants with Dose Limiting Toxicity (DLT)

    Measured over: Approximately 5 years 10 months

  • Part 1: Severity of DLT as Assessed by National Cancer Institute Common Terminology Criteria for Adverse Events (NCI-CTCAE)

    Measured over: Approximately 5 years 10 months

  • Part 2: Number of Participants with Adverse Events (AEs) and Serious Adverse Events (SAEs) as a Measure of Safety and Tolerability

    Measured over: Approximately 5 years 10 months

  • Part 2: Number of Participants with Adverse Events and SAEs by Severity

    Measured over: Approximately 5 years 10 months

  • Part 3: Overall Response Rate (ORR)

    Measured over: Approximately 5 years 10 months

Changes Tremor has spotted

No changes since Tremor started watching this trial.
Show details (technical version)

Score inputs

  • results_overdue: base 10, now 10, since 2025-03-18, no fading
  • insider_selling_cluster: base 5, now 2, since 2026-08-17, fades (half-life)

Raw record changes

  • none yet

Trial ID NCT04586426 · record last updated 2026-01-16 · checked 2026-11-09 15:47 UTC

See the official record on ClinicalTrials.gov (NCT04586426) ↗